推荐产品
生物来源
rat
重组
expressed in E. coli
检测方案
≥98% (SDS-PAGE)
形式
lyophilized
分子量
~38.4 kDa
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
NCBI登记号
运输
wet ice
储存温度
−20°C
基因信息
rat ... Vegfa(83785)
一般描述
VEGF165 (vascular endothelial growth factor 165), also known as VEGF-A, is a homodimeric glycoprotein and is expressed as multiple splice variants. Recombinant rat VEGF is a double, non-glycosylated, polypeptide containing 164 amino acids and having a molecular mass of 38.4kDa.
应用
VEGF165 (vascular endothelial growth factor 165) has been used to study the effects of VEGF on the morphology and survival of neurons and glial cells.
生化/生理作用
VEGF165 (vascular endothelial growth factor 165) has been shown to have pro-angiogenic properties. It has a role in the proliferation of endothelial cells and neuroprotection.
外形
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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Following spinal cord injury (SCI) there are drastic changes that occur in the spinal microvasculature, including ischemia, hemorrhage, endothelial cell death and blood-spinal cord barrier disruption. Vascular endothelial growth factor-A (VEGF-A) is a pleiotropic factor recognized for its pro-angiogenic properties;
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Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an overdose
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Vascular endothelial growth factor (VEGF) is a hallmark of glioblastoma multiforme (GBM) and plays an important role in brain development and function. Recently, it has been reported that treatment of GBM patients with bevacizumab, an anti-VEGF antibody, may cause a
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