推荐产品
生物来源
mouse
重组
expressed in E. coli
方案
≥98%
表单
lyophilized
效能
1.0-5 ng/mL
分子量
~39.0 kDa
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
NCBI登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Vegfa(22339)
一般描述
VEGF (vascular endothelial growth factor) is a homodimeric protein secreted by a variety of vascularized tissues. It is expressed embryonically in mice, in the lung mesenchyme and epithelium. It belongs to the group of vascular endothelium-specific growth factors. Mouse VEGF is a 39kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.
生化/生理作用
VEGF (vascular endothelial growth factor) stimulates endothelial cell growth, angiogenesis, vasculogenesis and capillary permeability. It has a role in the differentiation of mesenchymal stem cells into osteoblasts and adipocytes. Disruption of this gene in mice has been associated with vascular abnormalities.
外形
Lyophilized without any additives.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Anti-bevacizumab idiotype antibody vaccination is effective in inducing vascular endothelial growth factor-binding response, impairing tumor outgrowth.
Sanches Jde S
Cancer Science, 107(4), 551-555 (2016)
Vascular-specific growth factors and blood vessel formation.
Yancopoulos GD
Nature, 407(6801), 242-248 (2000)
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease.
Wieck MM
PLoS ONE, 11(2), e0148323-e0148323 (2016)
Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development.
Schlieve CR
PLoS ONE, 11(3), e0151396-e0151396 (2016)
Louisa Mezache et al.
Scientific reports, 10(1), 20463-20463 (2020-11-26)
Atrial fibrillation (AF) is the most common arrhythmia and is associated with inflammation. AF patients have elevated levels of inflammatory cytokines known to promote vascular leak, such as vascular endothelial growth factor A (VEGF). However, the contribution of vascular leak
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