产品名称
人白介素-3 人, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
biological source
human
recombinant
expressed in E. coli
assay
≥98% (HPLC)
≥98% (SDS-PAGE)
form
lyophilized
mol wt
~15.0 kDa
packaging
pkg of 10 μg
impurities
endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL3(3562)
Biochem/physiol Actions
白介素-3(IL2)是一种造血生长因子。编码它的基因位于人染色体5上。它在细胞增殖中起作用并激活不同的信号级联放大。它对于造血内皮祖细胞(EPC)的分化至关重要。IL-3刺激红细胞、肥大细胞和粒细胞的分化。该蛋白质与精神分裂症有关。
General description
IL-3 是一种物种特异性集落刺激因子,可刺激骨髓培养物中巨核细胞、中性粒细胞和巨噬细胞的集落形成。重组人IL-3是含有133个氨基酸残基的15.0kDa蛋白质。
Physical form
冻干品,无添加剂。
Preparation Note
打开样品瓶之前需离心。避免反复冻融。
用水配制成浓度为0.1-1.0 mg/mL的溶液。然后可以将该溶液稀释到其它水性缓冲液中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers.
Baxter EW
Journal of Immunology (2012)
IL-3 is a novel target to interfere with tumor vasculature.
Dentelli P
Oncogene (2011)
IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks.
Meyer CG
Human Molecular Genetics (2011)
The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors.
Luo XJ
PLoS ONE (2012)
Association of interleukin 3 (IL-3) polymorphisms with schizophrenia in Han Chinese population.
Liu Z
Neuroscience Letters (2015)
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