SRP3100
KGF 人
Animal-component free, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
别名:
HBGF-7, 成纤维细胞生长因子 7, 角质形成细胞生长因子
biological source
human
recombinant
expressed in E. coli
assay
≥95% (HPLC), ≥95% (SDS-PAGE)
form
lyophilized
potency
≤10 ng/mL ED50
mol wt
18.9 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
off-white to yellow
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF7(2252)
General description
成纤维细胞生长因子 7（FGF-7）是成纤维细胞生长因子家族的成员。FGF 家族成员具有广泛的促有丝分裂和细胞存活活性。编码该蛋白的基因位于人类染色体 15q21.1 上。
Biochem/physiol Actions
成纤维细胞生长因子（FGF）家族成员参与胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭等多种生物学过程。FGF7 是一种有效的上皮细胞特异性生长因子，其促有丝分裂活性主要表现在角质形成细胞中，而在成纤维细胞和内皮细胞中则没有。该蛋白质与成纤维细胞生长因子受体（FGFRs）结合并激活它们。对该基因的小鼠和大鼠同源物的研究表明，该基因在上皮的形态发生、伤口的表皮再生、头发的发育和早期肺器官发生等过程中起作用。
Physical form
从 15mM 磷酸钠，pH 7.0 + 0.25 M NaCl 中冻干。
Preparation Note
在打开之前将小瓶进行离心。用 1x PBS 进行重悬至浓度为 0.5-1.0 mg/ml。不要涡旋。该溶液可在2-8℃下储存最长达1周。如需更长时间的储存，建议使用含有稳定剂（如5％海藻糖）的缓冲液进行进一步的稀释，并在分装成工作体积后冻存在-20°C至-80°C。
Other Notes
MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
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