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安全信息

SRP2112

Sigma-Aldrich

TFIIB, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

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别名:
TF2B, TFIIB
UNSPSC代码:
12352202
NACRES:
NA.26

生物来源

human

重组

expressed in E. coli

检测方案

≥70% (SDS-PAGE)

形式

frozen liquid

分子量

~61.2 kDa

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

400 μg/mL

颜色

clear colorless

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... GTF2B(2959)

生化/生理作用

The transcription factor IIB (TFIIB) is an essential factor for transcription by RNA polymerase II. TFIIB has been shown to be required for selective binding of RNA polymerase II, TFIIF and TFIID-DNA complex, and for specifying the start site of transcription. Human TFIIB is a single, 35 kDa polypeptide, homologous to yeast factor, the product of the SUA7 gene.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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General initiation factors for RNA polymerase II.
R C Conaway et al.
Annual review of biochemistry, 62, 161-190 (1993-01-01)
S Malik et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(21), 9553-9557 (1991-11-01)
Transcription factor TFIIB is a ubiquitous factor required for transcription initiation by RNA polymerase II. Previous studies have suggested that TFIIB serves as a bridge between the "TATA"-binding factor (TFIID) and RNA polymerase II during preinitiation complex assembly and, more
The general transcription factors of RNA polymerase II.
G Orphanides et al.
Genes & development, 10(21), 2657-2683 (1996-11-01)

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