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Merck
CN
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主要文件

安全信息

SRP2106

Sigma-Aldrich

TATA box binding protein,GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

别名:

GTF2D, GTF2D1, HDL4, MGC117320, MGC126054, MGC126055, SCA17, TFIID

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.26

生物来源

human

重组

expressed in E. coli

方案

≥70% (SDS-PAGE)

表单

frozen liquid

分子量

~64.4 kDa

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

350 μg/mL

颜色

clear colorless

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... TBP(6908)

生化/生理作用

TBP is the core protein of the transcription factor IID complex, the multiprotein DNA-binding factor that coordinates activities necessary for initiation of transcription by RNA polymerase II.
The TATA-binding protein (TBP) is believed to function as an essential factor of the general transcription machinery and to be involved in transcription by all three eukaryotic RNA polymerases (pol I, II, and III). TBP specifically binds to the TATA element at the promoter region and interacts with numerous transcription factors, including TBP-associated factors (TAFs), activators, and some tumor suppressor proteins.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Horikoshi et al.
Cell, 54(7), 1033-1042 (1988-09-23)
The mammalian activator protein ATF stimulates transcription from the adenovirus E4 promoter by binding to multiple upstream promoter and enhancer elements. DNAase footprint analyses have revealed that there are cooperative interactions between ATF and TFIID (the mammalian TATA factor) when
TBP, a universal eukaryotic transcription factor?
N Hernandez
Genes & development, 7(7B), 1291-1308 (1993-07-01)
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies.
A Hoffmann et al.
Nucleic acids research, 19(22), 6337-6338 (1991-11-25)

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