生物来源
human
重组
expressed in E. coli
检测方案
≥90% (SDS-PAGE)
形式
aqueous solution
分子量
14.1 kDa
包装
pkg of 100 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... KAT2A(2648)
一般描述
Human GCN5 or KAT2A containing bromodomain (GenBank Accession No. NM_021078) amino-acids 727 – 837 (end) with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Shanshan Li et al.
The Journal of biological chemistry, 284(14), 9411-9417 (2009-02-17)
Bromodomains are acetyl lysine binding modules found in many complexes that regulate gene transcription. In budding yeast, the coactivator complex SAGA (Spt-Ada-Gcn5-acetyl-transferase) predominantly facilitates transcription of stress-activated genes and requires the bromodomain of the Gcn5 subunit for full activation of
Donna A Santillan et al.
Cancer research, 66(20), 10032-10039 (2006-10-19)
A critical unanswered question about mixed lineage leukemia (MLL) is how specific MLL fusion partners control leukemia phenotype. The MLL-cyclic AMP-responsive element binding protein-binding protein (CBP) fusion requires both the CBP bromodomain and histone acetyltransferase (HAT) domain for transformation and
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