生物来源
human
重组
expressed in E. coli
检测方案
≥90% (SDS-PAGE)
形式
aqueous solution
分子量
14.7 kDa
包装
pkg of 100 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... BRD4(23476)
一般描述
Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP (GenBank Accession No. NM_058243) amino-acids 342-460 with N-terminal His-tag, MW = 14.7 kDa, expressed in an E. coli expression system.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Philipp Voigt et al.
Genome biology, 12(11), 133-133 (2011-12-01)
The chromatin adapter BRD4 may be crucial for transmitting epigenetic information by acting as a histone acetylation-dependent gene bookmark and accelerating post-mitotic transcriptional reactivation.
R M Rodriguez et al.
Journal of molecular medicine (Berlin, Germany), 90(5), 587-595 (2011-11-29)
The bromodomain protein BRD4 is involved in cell proliferation and cell cycle progression, primarily through its role in acetylated chromatin-dependent regulation of transcription at targeted loci. Here, we show that BRD4 is frequently downregulated by aberrant promoter hypermethylation in human
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