生物来源
human
重组
expressed in E. coli
检测方案
≥90% (SDS-PAGE)
形式
aqueous solution
分子量
14.1 kDa
包装
pkg of 100 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... BRD3(8019)
一般描述
Human Bromodomain containing 3, also known as BRD3 or RING3L (GenBank Accession No. NM_007371) amino-acids 306 – 417 with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Roland Gamsjaeger et al.
Molecular and cellular biology, 31(13), 2632-2640 (2011-05-11)
Recent data demonstrate that small synthetic compounds specifically targeting bromodomain proteins can modulate the expression of cancer-related or inflammatory genes. Although these studies have focused on the ability of bromodomains to recognize acetylated histones, it is increasingly becoming clear that
Janine M Lamonica et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(22), E159-E168 (2011-05-04)
Acetylation of histones triggers association with bromodomain-containing proteins that regulate diverse chromatin-related processes. Although acetylation of transcription factors has been appreciated for some time, the mechanistic consequences are less well understood. The hematopoietic transcription factor GATA1 is acetylated at conserved
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