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Merck
CN
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主要文件

安全信息

SRP0442

Sigma-Aldrich

UEV1A active human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

别名:

CIR1, CROC1, UBE2V1, ubiquitin-conjugating enzyme E2 variant 1

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

方案

≥80% (SDS-PAGE)

表单

aqueous solution

分子量

20 kDa

包装

pkg of 100 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... UBE2V1(7335)

一般描述

UEV1A (ubiquitin-conjugating enzyme E2 variant 1), also known as UBE2V1 or CROC-1 (GenBank Accession No. NM_021988) amino acids 2-170 (end) with N-terminal FLAG-tag, MW=20 kDa, expressed in E. coli.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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L Ma et al.
Oncogene, 17(10), 1321-1326 (1998-10-15)
Acquisition of the immortal phenotype by tumor cells represents an essential and potentially rate-limiting step in tumorigenesis. To identify changes in gene expression that are associated with the early stages of cell immortalization, we compared genetically matched pairs of pre-immortal
T M Thomson et al.
FEBS letters, 423(1), 49-52 (1998-05-15)
The open reading frame YGL087c in the budding yeast Saccharomyces cerevisiae genome encodes a polypeptide highly similar to the human UEV (ubiquitin-conjugating E2 enzyme variant) proteins, which have been proposed to belong to a family of putative dominant negative ubiquitin
Jing Geng et al.
Nature immunology, 16(11), 1142-1152 (2015-09-29)
Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample reactive oxygen species (ROS) in phagocytes to kill pathogens. However, how phagosomes transmit signals to recruit mitochondria has remained unclear. Here we found that the kinases Mst1
D Duong Hau et al.
Biochemistry, 45(32), 9866-9877 (2006-08-09)
Lys(63)-linked polyubiquitination of TRAF2 or TRAF6 is an essential step within the signal transduction cascade responsible for activation of p38, c-Jun N-terminal kinase, and the transcription factor NF-kappaB. Attachment of ubiquitin (Ub) to a TRAF, and conjugation of Ub molecules

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