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Merck
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主要文件

安全信息

SRP0429

Sigma-Aldrich

PDE4A10 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE)

别名:

DPDE2, PDE46, phosphodiesterase 4A, cAMP-specific

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

方案

≥75% (SDS-PAGE)

表单

aqueous solution

比活

≥75% (compared to standard)

分子量

117 kDa

包装

pkg of 10 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PDE4A(5141)

一般描述

Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW= 117 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

单位定义

One unit is defined as the amount of enzyme that will convert 1 pmole of 3?, 5?-cAMP to 5?-AMP per min at 37°C.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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I McPhee et al.
Cellular signalling, 13(12), 911-918 (2001-12-01)
In situ hybridisation methods were used to map the distribution of the novel long PDE4A10 isoform in the brain. PDE4A10 distribution was compared to that of the long PDE4A5 isoform and the short PDE4A1 isoform using probes specific for unique
Angela McCahill et al.
Cellular signalling, 20(11), 2071-2083 (2008-08-30)
Transcripts for the PDE4A10 cyclic AMP phosphodiesterase isoform are present in a wide variety of rat tissues including the heart. Sequence comparisons between the putative human and mouse promoters revealed a number of conserved regions including both an Sp1 and

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