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安全信息

SRP0418

Sigma-Aldrich

WDR5 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

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别名:
BIG-3, SWD3, WD Repeat Domain 5
UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

检测方案

≥90% (SDS-PAGE)

形式

aqueous solution

分子量

37.5 kDa

包装

pkg of 100 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... WDR5(11091)

一般描述

Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3 (GenBank Accession No. NM_017588) amino acids 2-334 (end) with N-terminal His-tag, MW=37.5 kDa, expressed in Sf9 insect cells via a Baculovirus expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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WDR5, a complexed protein.
Raymond C Trievel et al.
Nature structural & molecular biology, 16(7), 678-680 (2009-07-07)
Yan-Yi Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(2), 815-820 (2010-01-19)
Viral infection causes activation of the transcription factors NF-kappaB and IRF3, which collaborate to induce type I interferons (IFNs) and cellular antiviral response. The mitochondrial outer membrane protein VISA acts as a critical adapter for assembling a virus-induced complex that
Zain Odho et al.
The Journal of biological chemistry, 285(43), 32967-32976 (2010-08-19)
Histone modification is well established as a fundamental mechanism driving the regulation of transcription, replication, and DNA repair through the control of chromatin structure. Likewise, it is apparent that incorrect targeting of histone modifications contributes to misregulated gene expression and

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