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方案
≥95% (HPLC)
表单
aqueous solution
包装
pkg of 500 μL
浓度
40 μM
运输
dry ice
储存温度
−70°C
一般描述
Histone H3 peptide mono-methylated at Lysine 9, biotinylated, substrate for histone demethylases belonging to the Jumanji domain-containing (JMJ) family .
应用
Suitable as a substrate for histone demethylases belonging to the Jumonji (JMJ) family. It can be used to study enzyme kinetics, and to screen small molecular inhibitors of these demethylases for drug discovery and HTS applications.
其他说明
500 μL at 40 μM, or 20 nmol Sold as 500 μL
储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Shiv I S Grewal et al.
Current opinion in cell biology, 16(3), 230-238 (2004-05-18)
Heterochromatin mediates various nuclear processes including centromere function, gene silencing and nuclear organization. Although it was discovered nearly 75 years ago, the pathways involved in heterochromatin establishment, assembly and epigenetic maintenance have been elusive. Recent reports have demonstrated that distinct
Judd C Rice et al.
Molecular cell, 12(6), 1591-1598 (2003-12-24)
The functional significance of mono-, di-, and trimethylation of lysine residues within histone proteins remains unclear. Antibodies developed to selectively recognize each of these methylated states at histone H3 lysine 9 (H3 Lys9) demonstrated that mono- and dimethylation localized specifically
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