生物来源
human
重组
expressed in baculovirus infected Sf9 cells
检测方案
≥88% (SDS-PAGE)
形式
aqueous solution
分子量
114 kDa (EZH2)
48 kDa (RbAP48)
87 kDa (SUZ12)
包装
pkg of 20 μg
运输
dry ice
储存温度
−70°C
基因信息
human ... EZH2(2146) , RBBP4(5928) , SUZ12(23512)
一般描述
Complex of human EZH2 (GenBank Accession No. NM_004456) amino acids 2-end with N-terminal His-GST tag, MW= 114kDa; human SUZ12 (GenBank Accession No. NM_015355) amino acids 1-end with N-terminal His-tag, MW = 87kDa, and human RbAp48 (GenBank Accession No. NM_005610) amino acids 2-end with N-terminal His-tag, MW= 48 kDa, co-expressed in Baculovirus expression system.
外形
Formulated in 40 mM Tris-HCl, pH 8.0, 110mM NaCl, 2.2 mM KCl, 18 mM Glutathione, 3mM DTT, and 20% glycerol.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Rakotobe, D. et al.
Journal of Virology, 5, 32-32 (2008)
Sooryanarayana Varambally et al.
Science (New York, N.Y.), 322(5908), 1695-1699 (2008-11-15)
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of target genes and regulates the survival and metastasis of cancer cells. EZH2 is overexpressed in aggressive solid tumors by mechanisms that remain
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