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安全信息

SRP0383

Sigma-Aldrich

EHMT1 human

recombinant, expressed in E. coli, ≥63% (SDS-PAGE)

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别名:
EHMT1, KMT1D
UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

检测方案

≥63% (SDS-PAGE)

形式

aqueous solution

分子量

72.4 kDa

包装

pkg of 50 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... EHMT1(79813)

一般描述

Human euchromatic histone-lysine N-methyltransferase (EHMT1), also known as G9a-like protein (GLP) or KMT1D, (GenBank Accession No. NM_024757), amino acids 894-1298 (end) with N-terminal GST-tag, MW= 72.4 kDa, expressed in an E. coli expression system.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Glucagon-like peptide-1 (GLP-1) agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors produce some beneficial and deleterious effects in diabetic patients not mediated by their glycemic lowering effects, and there is a need for better understanding of the molecular basis of these effects.
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In the context of drug design, C-H···O hydrogen bonds have received little attention so far, mostly because they are considered weak relative to other noncovalent interactions such as O-H···O hydrogen bonds, π/π interactions, and van der Waals interactions. Herein, we
Levi Todd et al.
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Retinal progenitors in the circumferential marginal zone (CMZ) and Müller glia-derived progenitors have been well described for the eyes of fish, amphibians, and birds. However, there is no information regarding a CMZ and the nature of retinal glia in species
Jing Huang et al.
The Journal of biological chemistry, 285(13), 9636-9641 (2010-02-02)
The tumor suppressor p53 is regulated by numerous post-translational modifications. Lysine methylation has recently emerged as a key post-translational modification that alters the activity of p53. Here, we describe a novel lysine methylation site in p53 that is carried out
Jun Ueda et al.
The Journal of biological chemistry, 281(29), 20120-20128 (2006-05-17)
G9a is a SET-domain mammalian histone methyltransferase responsible for mono- and dimethylation of lysine 9 in histone H3 (H3K9) at euchromatic regions. Recently we reported that G9a forms a stoichiometric heteromeric complex with another SET-domain-containing molecule, GLP/Eu-HMTase1. Although G9a and

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