SRP0369
MNK1 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
别名:
MAP kinase interacting serine/threonine kinase 1
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关于此项目
Assay:
≥70% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
产品名称
MNK1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥70% (SDS-PAGE)
form
aqueous solution
mol wt
74 kDa
packaging
pkg of 10 μg
manufacturer/tradename
Croda International PLC
technique(s)
activity assay: suitable
inhibition assay: suitable
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... MKNK1(8569)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Human MNK (T385D) (GenBank Accession No. NM_003684), amino acids 2-End (amino acid deletion 165-205) with N-terminal GST-tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Physical form
Solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% TWEEN®-20, 30% glycerol, and 3 mM DTT.
Legal Information
TWEEN is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Bong Seok Kang et al.
Journal of cellular biochemistry, 118(8), 2357-2370 (2017-01-21)
ERK1 and ERK2 share a great deal of homology and have been presumed to have similar functions. Available antibodies recognize both isoforms making the elucidation of functional differences challenging. Mitogen-activated protein (MAP) kinase networks are commonly depicted in the literature
Theodore Vougiouklakis et al.
Oncotarget, 6(41), 43162-43171 (2015-11-21)
The oncogenic protein ERK, a member of the extracellular signal-regulated kinase (ERK) cascade, is a well characterized signaling molecule involved in tumorigenesis. The ERK signaling pathway is activated in a large proportion of cancers and plays a critical role in
Seung-Hee Chang et al.
American journal of respiratory cell and molecular biology, 35(5), 528-539 (2006-06-10)
Inorganic phosphate (Pi) plays a critical role in diverse cellular functions. Among three classes of sodium/phosphate co-transporters (NPTs), two types have been identified in mammalian lung. The potential importance of Pi as a novel signaling molecule and pulmonary expression of
Aaron James F Reyes et al.
Analytica chimica acta, 1155, 338341-338341 (2021-03-27)
Dysregulation of phosphorylation-mediated signaling drives the initiation and progression of many diseases. A substrate-specific kinase assay capable of quantifying the altered site-specific phosphorylation of its phenotype-dependent substrates provides better specificity to monitor a disease state. We report a sensitive and
S G Gregory et al.
Nature, 441(7091), 315-321 (2006-05-20)
The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1. Chromosome 1 is gene-dense, with 3,141 genes and 991 pseudogenes
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