生物来源
human
重组
expressed in baculovirus infected Sf9 cells
方案
≥70% (SDS-PAGE)
表单
aqueous solution
分子量
74 kDa
包装
pkg of 10 μg
制造商/商品名称
Croda International PLC
技术
activity assay: suitable
inhibition assay: suitable
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... MKNK1(8569)
一般描述
Human MNK (T385D) (GenBank Accession No. NM_003684), amino acids 2-End (amino acid deletion 165-205) with N-terminal GST-tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
外形
Solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% TWEEN®-20, 30% glycerol, and 3 mM DTT.
法律信息
TWEEN is a registered trademark of Croda International PLC
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
从最新的版本中选择一种：
Bong Seok Kang et al.
Journal of cellular biochemistry, 118(8), 2357-2370 (2017-01-21)
ERK1 and ERK2 share a great deal of homology and have been presumed to have similar functions. Available antibodies recognize both isoforms making the elucidation of functional differences challenging. Mitogen-activated protein (MAP) kinase networks are commonly depicted in the literature
Theodore Vougiouklakis et al.
Oncotarget, 6(41), 43162-43171 (2015-11-21)
The oncogenic protein ERK, a member of the extracellular signal-regulated kinase (ERK) cascade, is a well characterized signaling molecule involved in tumorigenesis. The ERK signaling pathway is activated in a large proportion of cancers and plays a critical role in
Seung-Hee Chang et al.
American journal of respiratory cell and molecular biology, 35(5), 528-539 (2006-06-10)
Inorganic phosphate (Pi) plays a critical role in diverse cellular functions. Among three classes of sodium/phosphate co-transporters (NPTs), two types have been identified in mammalian lung. The potential importance of Pi as a novel signaling molecule and pulmonary expression of
Aaron James F Reyes et al.
Analytica chimica acta, 1155, 338341-338341 (2021-03-27)
Dysregulation of phosphorylation-mediated signaling drives the initiation and progression of many diseases. A substrate-specific kinase assay capable of quantifying the altered site-specific phosphorylation of its phenotype-dependent substrates provides better specificity to monitor a disease state. We report a sensitive and
S G Gregory et al.
Nature, 441(7091), 315-321 (2006-05-20)
The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1. Chromosome 1 is gene-dense, with 3,141 genes and 991 pseudogenes
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