生物来源
human
重组
expressed in baculovirus infected Sf9 cells
方案
≥70% (SDS-PAGE)
表单
aqueous solution
分子量
91 kDa
包装
pkg of 10 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... CHEK2(11200)
一般描述
Human Checkpoint kinase 2 (GenBank Accession No. NM_007194), full length with N-terminal HIS-tag, MW=91kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Travis H Stracker et al.
Cell cycle (Georgetown, Tex.), 7(23), 3618-3621 (2008-11-26)
Central to the DNA damage response (DDR) is the highly conserved Mre11 complex consisting of Mre11, Rad50 and Nbs1. The Mre11 complex acts as a sensor of DNA double-strand breaks (DSBs) and regulates the signal transduction cascades that are triggered
Reinhardt HC and Yaffe MB.
Current Opinion in Cell Biology (2009)
Qi-Qiang Guo et al.
The EMBO journal, 39(10), e103111-e103111 (2020-03-19)
The homeostatic link between oxidative stress and autophagy plays an important role in cellular responses to a wide variety of physiological and pathological conditions. However, the regulatory pathway and outcomes remain incompletely understood. Here, we show that reactive oxygen species
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