SRP0350
IGF-1R active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
别名:
IGF1A, IGFI, insulin-like growth factor 1 (somatomedin C)
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Form:
aqueous solution
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
72.3 kDa (46 + GST-tag)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
72.3 kDa (46 + GST-tag)
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
0.32 mg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... IGF1(3479)
General description
Human IGFR1 (GenBank Accession No. NP_000875) , residues 930-1337 with N-terminal GST-fusion protein containing the 46 kDa cytoplasmic domain of the beta-subunit of the human Insulin-like Growth Factor-1 Receptor Kinase, MW=72.3 kDa, expressed in a Baculovirus expression system.
Application
Enzyme kinetics, autophosphorylation, and phosphorylation of target substrates.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
兴奋剂肽类激素
此项目有
K Baer et al.
Biochemistry, 40(47), 14268-14278 (2001-11-21)
To study the role of kinase dimerization in the activation of the insulin receptor (IR) and the insulin-like growth factor receptor-1 (IGF-1R), we have cloned, expressed, and purified monomeric and dimeric forms of the corresponding soluble kinase domains via the
N. Tennagels, et al.
Biochemical and Biophysical Research Communications, 260, 7-7 (1999)
Shin-Taek Oh et al.
The American Journal of dermatopathology, 36(10), 807-811 (2014-07-08)
Insulin-like growth factor-1 receptor (IGF-1R) is a key regulator of cell transformation and controls the expression of genes that governs cell cycling and cell survival. The aim of this pilot study was to gain insight into the expression pattern of
Ying Xia et al.
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Full-thickness skin injury affects millions of people worldwide each year. Although bone marrow-derived mesenchymal stem cells (BM-MSCs) have been shown to promote cutaneous wound healing, they cannot functionally promote wound healing with the recovery of appendages such as hair follicles.
Michiko Shigyo et al.
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