生物来源
human
重组
expressed in baculovirus infected Sf9 cells
检测方案
≥80% (SDS-PAGE)
形式
aqueous solution
分子量
72.3 kDa (46 + GST-tag)
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
浓度
0.32 mg/mL
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... IGF1(3479)
一般描述
Human IGFR1 (GenBank Accession No. NP_000875) , residues 930-1337 with N-terminal GST-fusion protein containing the 46 kDa cytoplasmic domain of the beta-subunit of the human Insulin-like Growth Factor-1 Receptor Kinase, MW=72.3 kDa, expressed in a Baculovirus expression system.
应用
Enzyme kinetics, autophosphorylation, and phosphorylation of target substrates.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
胰岛素激素类产品
常规特殊物品
Biochemistry, 40(47), 14268-14278 (2001-11-21)
To study the role of kinase dimerization in the activation of the insulin receptor (IR) and the insulin-like growth factor receptor-1 (IGF-1R), we have cloned, expressed, and purified monomeric and dimeric forms of the corresponding soluble kinase domains via the
Biochemical and Biophysical Research Communications, 260, 7-7 (1999)
The American Journal of dermatopathology, 36(10), 807-811 (2014-07-08)
Insulin-like growth factor-1 receptor (IGF-1R) is a key regulator of cell transformation and controls the expression of genes that governs cell cycling and cell survival. The aim of this pilot study was to gain insight into the expression pattern of
American journal of translational research, 12(10), 6264-6276 (2020-11-17)
Full-thickness skin injury affects millions of people worldwide each year. Although bone marrow-derived mesenchymal stem cells (BM-MSCs) have been shown to promote cutaneous wound healing, they cannot functionally promote wound healing with the recovery of appendages such as hair follicles.
Scientific reports, 5, 12055-12055 (2015-07-15)
Vimentin, an intermediate filament protein, is generally recognised as an intracellular protein. Previously, we reported that vimentin was secreted from astrocytes and promoted axonal growth. The effect of extracellular vimentin in neurons was a new finding, but its signalling pathway
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