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安全信息

SRP0350

Sigma-Aldrich

IGF-1R active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

别名:

IGF1A, IGFI, insulin-like growth factor 1 (somatomedin C)

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

检测方案

≥80% (SDS-PAGE)

形式

aqueous solution

分子量

72.3 kDa (46 + GST-tag)

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

0.32 mg/mL

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... IGF1(3479)

一般描述

Human IGFR1 (GenBank Accession No. NP_000875) , residues 930-1337 with N-terminal GST-fusion protein containing the 46 kDa cytoplasmic domain of the beta-subunit of the human Insulin-like Growth Factor-1 Receptor Kinase, MW=72.3 kDa, expressed in a Baculovirus expression system.

应用

Enzyme kinetics, autophosphorylation, and phosphorylation of target substrates.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

胰岛素激素类产品
常规特殊物品

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K Baer et al.
Biochemistry, 40(47), 14268-14278 (2001-11-21)
To study the role of kinase dimerization in the activation of the insulin receptor (IR) and the insulin-like growth factor receptor-1 (IGF-1R), we have cloned, expressed, and purified monomeric and dimeric forms of the corresponding soluble kinase domains via the
N. Tennagels, et al.
Biochemical and Biophysical Research Communications, 260, 7-7 (1999)
Shin-Taek Oh et al.
The American Journal of dermatopathology, 36(10), 807-811 (2014-07-08)
Insulin-like growth factor-1 receptor (IGF-1R) is a key regulator of cell transformation and controls the expression of genes that governs cell cycling and cell survival. The aim of this pilot study was to gain insight into the expression pattern of
Ying Xia et al.
American journal of translational research, 12(10), 6264-6276 (2020-11-17)
Full-thickness skin injury affects millions of people worldwide each year. Although bone marrow-derived mesenchymal stem cells (BM-MSCs) have been shown to promote cutaneous wound healing, they cannot functionally promote wound healing with the recovery of appendages such as hair follicles.
Michiko Shigyo et al.
Scientific reports, 5, 12055-12055 (2015-07-15)
Vimentin, an intermediate filament protein, is generally recognised as an intracellular protein. Previously, we reported that vimentin was secreted from astrocytes and promoted axonal growth. The effect of extracellular vimentin in neurons was a new finding, but its signalling pathway

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