生物来源
human
重组
expressed in baculovirus infected Sf9 cells
检测方案
≥80% (SDS-PAGE)
形式
aqueous solution
分子量
52 kDa
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
浓度
0.5 mg/mL
技术
activity assay: suitable
inhibition assay: suitable
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... EPHB2(2048)
一般描述
Human EPHB2 ( GenBank Accession No. NM_004442), amino acids 569-end with N-terminal His-tag, MW=52 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Hongshi Xu et al.
American journal of physiology. Renal physiology, 288(4), F855-F866 (2004-11-25)
EphA2, a member of the large family of Eph receptor tyrosine kinases, is highly expressed in epithelial tissue and has been implicated in cell-cell and cell-matrix interactions, as well as cell growth and survival. Expression of EphA2 mRNA and protein
Madhu Macrae et al.
Cancer cell, 8(2), 111-118 (2005-08-16)
The EphA2 receptor tyrosine kinase is frequently overexpressed in many cancers, including 40% of breast cancers. Here, we show that EphA2 is a direct transcriptional target of the Ras-Raf-MAPK pathway and that ligand-stimulated EphA2 attenuates the growth factor-induced activation of
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