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主要文件

安全信息

SRP0337

Sigma-Aldrich

Tyk2 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

别名:

JTK1, tyrosine kinase 2

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About This Item

UNSPSC代码:
12352204
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

方案

≥90% (SDS-PAGE)

表单

aqueous solution

分子量

38 kDa

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

0.18 mg/mL

技术

activity assay: suitable
inhibition assay: suitable

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... TYK2(7297)

一般描述

Human Tyk2 (Tyrosine Kinase 2, also known as JTK1), (GenBank Accession No. NM_003331), amino acids 871-1187 (end) with N-terminal His-tag, MW=38 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Repr. 1B

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Partanen J, et al.
Proceedings of the National Academy of Sciences of the USA, 87, 8913-8917 (1991)
P Domanski et al.
FEBS letters, 374(3), 317-322 (1995-11-06)
The Jak kinases and Stat transcription factors play a major role in signaling of various cytokines including IFN alpha. In this report we show a ligand-independent interaction between Tyk-2 and Jak-1 kinases. We also demonstrate that the Tyk-2 kinase forms
I Firmbach-Kraft et al.
Oncogene, 5(9), 1329-1336 (1990-09-01)
We previously identified a novel protein tyrosine kinase gene, tyk2, by screening a human lymphoid cDNA library with a tyrosine kinase domain specific c-fms restriction fragment under low stringency hybridization conditions. We have now isolated and sequenced a full length

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