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Merck
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主要文件

安全信息

SRP0328

Sigma-Aldrich

PADI-3 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

别名:

Peptidyl arginine deiminase, type III

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

方案

≥60% (SDS-PAGE)

表单

aqueous solution

分子量

75 kDa

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

浓度

0.25 mg/mL

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PADI3(51702)

一般描述

Human PADI-3, also known as Peptidyl arginine deiminase, type III, (GenBank Accession No. NM_016233), amino acids 1-664 (end) with C-terminal FLAG-tag, MW= 75 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Sijun Dong et al.
The Biochemical journal, 397(3), 449-459 (2006-05-05)
Human peptidylarginine deiminase type III gene (PADI3) encodes a crucial post-translational modification enzyme that converts protein-bound arginine residues into citrulline residues. Its expression is restricted to a few cell types, including keratinocytes in the granular layer of the epidermis and
T Kanno et al.
The Journal of investigative dermatology, 115(5), 813-823 (2000-11-09)
Peptidylarginine deiminase catalyzes the post-translational modification of proteins through the conversion of arginine to citrulline in the presence of calcium ions. In rodents, peptidylarginine deiminase has been classified into four isoforms, types I, II, III, and IV, which are distinct
Rachida Nachat et al.
The Journal of investigative dermatology, 124(2), 384-393 (2005-01-29)
Post-translational conversion of arginine to citrulline residues is catalyzed by peptidylarginine deiminases (PAD). Although the existence of five isoforms of PAD has been reported in rodents and humans, their tissue distribution, substrate specificity, and physiological function have yet to be

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