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Merck
CN

SML3910

Sigma-Aldrich

Yoda2

≥98% (HPLC)

别名:

KC289, Potassium 4-(5-((2,6-dichlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)benzoate, Yoda1 Analog KC289

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About This Item

经验公式(希尔记法):
C16H9Cl2KN2O2S2
分子量:
435.39
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (Warmed)

储存温度

2-8°C

生化/生理作用

Highly selective and potent agonist Piezo1, analog of Yoda1.



Yoda2 is a highly selective analog of Piezo1 agonist Yoda1 that exhibits improved potency, selectivity, solubility, stability, and efficacy.

注意

Hygroscopic

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gregory Parsonage et al.
British journal of pharmacology, 180(16), 2039-2063 (2022-12-03)
The protein PIEZO1 forms mechanically activated, calcium-permeable, non-selective cation channels in numerous cell types from several species. Options for pharmacological modulation are limited and so we modified a small-molecule agonist at PIEZO1 channels (Yoda1) to increase the ability to modulate

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