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生化/生理作用
Cell penetrant and potent phospholipase A2 (PLA2) inhibitor
Fuzapladib (IS-741) is a cell penetrant and potent phospholipase A2 (PLA2) inhibitor. Fuzapladib decelerate the progression of pancreatic fibrosis through monocyte infiltration in dogs.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Nanocrystal solid dispersion of fuzapladib free acid with improved oral bioavailability
Biopharmaceutics & Drug Disposition, 43(3), 89-97 (2022)
Effect of IS-741 on ethionine-induced acute pancreatitis in rats: relation to pancreatic acinar cell regeneration
Journal of Gastroenterology, 38(3), 260-267 (2003)
Effects of IS-741, a synthetic anti-inflammatory agent, on bleomycin-induced lung injury in mice
Lung, 187(5), 331-339 (2009)
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