SML3863
Tecovirimat
≥98% (HPLC)
别名:
4-Trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide, SIGA-246, ST-246, rel-N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)benzamide
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About This Item
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生化/生理作用
Antiviral with activity against orthopoxviruses such as cowpox and monkeypox and including smallpox
Tecovirimat (ST-246) is an antiviral with activity against orthopoxviruses such as cowpox and monkeypox and including smallpox. Tecovirimat inhibits the function of a major envelope protein required for the production of extracellar virus, prevented the virus from leaving the cell, and spreading within the body. FDA-approved for the treatment of human smallpox disease caused by Variola virus in adults and children.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Fragment-Based Approaches Identified Tecovirimat-Competitive Novel Drug Candidate for Targeting the F13 Protein of the Monkeypox Virus
Viruses, 15(2), 570-570 (2023)
Emergence of cowpox: study of the virulence of clinical strains and evaluation of antivirals
PLoS ONE, 8(2), e55808-e55808 (2013)
Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox)
Antimicrobial Agents and Chemotherapy, 57(12), 6246-6253 (2013)
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