所有图片(1)
别名:
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt, Cefditoren Acid Sodium Salt, ME 1206 sodium salt
经验公式（希尔记法）:
C19H17N6NaO5S3
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质量水平
检测方案
≥95% (HPLC)
形式
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear (Warmed)
储存温度
-10 to -25°C
生化/生理作用
Cefditoren sodium is orally available, broad spectrum third-generation cephalosporin antibiotic. Cefditoren sodium is active against both gram-negative and gram-positive bacteria. It is commonly used for treatment of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections.
注意
Hygroscopic
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats
The Journal of Pharmacy and Pharmacology, 70(11), 1503-1512 (2018)
Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model
PLoS ONE, 5(8) (2010)
A Tamura et al.
Antimicrobial agents and chemotherapy, 32(9), 1421-1426 (1988-09-01)
ME1207 (pivaloyloxymethyl ester of ME1206) is a new oral cephalosporin. ME1206 is (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)- acetamido]-3-[(Z)-2-(4-methylthiazol-5-yl)-ethyl]-cephem-4-carboxy lic acid. The susceptibilities of about 1,600 clinical isolates to ME1206 were determined by the agar dilution method. ME1206 showed a broad spectrum of activity against
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