所有图片(2)
别名:
(1α,3β,5α)-3-[(hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium] chloride, Azoniaspiro(3α-benziloyloxynortropane-8,1′-pyrrolidine) chloride
经验公式（希尔记法）:
C25H30NO3·Cl
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质量水平
检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear (Warmed)
储存温度
-10 to -25°C
生化/生理作用
Trospium chloride is a peripheral muscarinic receptor antagonist that relaxes the smooth muscle in the bladder. It does ot cause central nervous system side effects typical for other drugs of its class. Trospium chloride is used for the treatment of overactive bladder.
注意
Hygroscopic
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Cognitive Effects of Anticholinergic Load in Women with Overactive Bladder
Clinical Interventions in Aging, 15, 1493-1503 (2020)
Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial
The Journal of Urology, 171(6 Pt 1), 2311-2315 (2004)
Kelly Biastre et al.
The Annals of pharmacotherapy, 43(2), 283-295 (2009-02-06)
To review the pharmacology, pharmacokinetics, safety, and clinical application of trospium chloride for the management of overactive bladder (OAB). Clinical literature including both primary sources and review articles was accessed through MEDLINE, International Pharmaceutical Abstracts, and Cochrane databases from 1980
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