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Merck
CN

SML3786

Sigma-Aldrich

Polaprezinc

≥97% (Zinc Elemental Analysis)

别名:

(N-(3-aminopropionyl)-L-histidinato zinc, N-β-Alanyl- L-histidine zinc complex, Zinc L-carnosine, beta-alanyl-L-histidinato zinc

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About This Item

经验公式(希尔记法):
C9H12N4O3Zn
分子量:
289.61
UNSPSC代码:
12352200
NACRES:
NA.21

质量水平

方案

≥97% (Zinc Elemental Analysis)

表单

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

-10 to -25°C

SMILES字符串

[Zn]1N([C@H](C(=O)O1)Cc2[nH]cnc2)C(=O)CCN

InChI key

IGXZLYMCFZHNKW-FJXQXJEOSA-L

生化/生理作用

Polaprezinc is an orally available Zinc L-carnosine complex. It is a mucosal protective agent that exhibits ROS-quenching activities, which promotes the repair of damaged tissues. Polaprezinc exerts cytoprotection through stimulation of Hsp70 expression that prevents the development of inflammatory process in the large intestinal mucosa. It is approved in Japan and Korea for treatment of gastric ulcers.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Role of nutritional zinc in the prevention of osteoporosis
Molecular and Cellular Biochemistry, 338(1-2), 241-254 (2010)
Antioxidant, Anti-inflammatory, and Genomic Stability Enhancement Effects of Zinc l-carnosine: A Potential Cancer Chemopreventive Agent
Nutrition and Cancer, 69(2), 201-210 (2017)
Drug repositioning of polaprezinc for bone fracture healing
Communications biology, 5(1), 462-462 (2022)

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