SML3767
AA-263
≥98% (HPLC)
别名:
2-Hydroxybenzaldehyde 2-(4-nitrophenyl)hydrazone, NSC 101540, Salicylaldehyde 4-nitrophenylhydrazone, o-Hydroxybenzaldehyde p-nitrophenylhydrazone
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C13H11N3O3
化学文摘社编号:
分子量:
257.24
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
[N+](=O)([O-])c1ccc(cc1)N\N=C\c2c(cccc2)O
InChI
1S/C13H11N3O3/c17-13-4-2-1-3-10(13)9-14-15-11-5-7-12(8-6-11)16(18)19/h1-9,15,17H/b14-9+
InChI key
VQIJGQPVYQKSSH-NTEUORMPSA-N
assay
≥98% (HPLC)
form
powder
color
, Faint orange to Red
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
AA-263 is a cell penetrant, potent and selective ATF6 activator that corrects the trafficking, conformation, secretion, and function of AAT-Z. AA-263 increases AAT neutrophil elastase (NE) inhibitory activity, while reducing polymer accumulation for the majority of AATD (alpha-1 antitrypsin (AAT) causes AAT deficiency) variants.
Cell penetrant, potent and selective ATF6 activator that corrects the trafficking, conformation, secretion, and function of AAT-Z
wgk
WGK 3
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis
Cell Chemical Biology, 30(1) (2023)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持