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Merck
CN

SML3504

Sigma-Aldrich

AM-2201

≥98% (HPLC)

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别名:
1-(5-Fluoropentyl)-3-(1-naphthoyl) indole, AM 2201, JWH 2201, [1-(5-Fluoropentyl)-1H-indol-3-yl]-1-naphthalenylmethanone
经验公式(希尔记法):
C24H22FNO
分子量:
359.44
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

药品控制

USDEA Schedule I

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

运输

wet ice

储存温度

-10 to -25°C

SMILES字符串

O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(C4=CC=CC=C43)CCCCCF

InChI

1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

InChI key

ALQFAGFPQCBPED-UHFFFAOYSA-N

生化/生理作用

AM-2201 is a potent agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 1.0nM at CB1 and 2.6nM at CB2. AM-2201 is more potent than phytocannabinoid Δ9-tetrahydrocannabinol.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Stefan Kneisel et al.
Journal of mass spectrometry : JMS, 47(7), 825-835 (2012-07-14)
The analysis of synthetic cannabinoids in human matrices is of particular importance in the fields of forensic and clinical toxicology since cannabis users partly shift to the consumption of 'herbal mixtures' as a legal alternative to cannabis products in order
Jeremy Carlier et al.
The Journal of pharmacology and experimental therapeutics, 367(3), 543-550 (2018-09-30)
Novel synthetic cannabinoids are appearing in recreational drug markets worldwide. Pharmacological characterization of these new drugs is needed to inform clinicians, toxicologists, and policy makers who monitor public health. [1-(5-Fluoropentyl)-1H-indol-3-yl](1-naphthyl)methanone (AM-2201) is an abused synthetic cannabinoid that was initially created
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites.
Xingxing Diao
Frontiers in Chemistry, 7, 109-109 (2019)

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