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COO原产地证书/COA分析证书

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SML3494

β-Benzamide adenine dinucleotide sodium salt

Name: β-Benzamide adenine dinucleotide sodium salt
Brand: SIGMA

≥95% (HPLC)

别名:

Adenosine 5′-(trihydrogen diphosphate) P′→5′-ester with 3-β-D-ribofuranosylbenzamide sodium salt, BAD, benzamide adenine dinucleotide sodium salt

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About This Item

经验公式（希尔记法）:

C₂₂H₂₆N₆O₁₄P₂Na₂

分子量:

706.40

UNSPSC代码:

51111800

NACRES:

NA.77

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质量水平

100

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

储存温度

-10 to -25°C

SMILES字符串

O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N(C=N3)C4=C3C(N)=NC=N4)O2)(O[Na])=O)(O[Na])=O)O[C@H]1C5=CC(C(N)=O)=CC=C5

生化/生理作用

β-Benzamide adenine dinucleotide (BAD), an analogue of nicotinamide adenine dinucleotide (β-NAD+), is an active metabolite of benzamide riboside and a potent inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH). Also, β-Benzamide adenine dinucleotide is a non-hydrolysable substrate/inhibitor of NADases and PARP enzymes. A higher concentration (Ki = 90 μM) it inhibits human NAD kinase.

Analogue of nicotinamide adenine dinucleotide (β-NAD+); inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH)