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生化/生理作用
Brivaracetam shows approximately 10 times greater potency than levetiracetam (Keppra)*; pIC50 at LBS = 7.0; inhibits audiogenic seizures in seizure-prone mice (ED50 = 14 μmol/kg) and is also effective in other animal models of epilepsy. Brivaracetam is used as an anticonvulsant (antiepileptic) for seizure treatment.
Orally active levetiracetam analog with higher synaptic vesicle protein 2A (SV2A) affinity and >10 times greater in vivo antiseizure efficay.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus
Journal of neural transmission (Vienna, Austria : 1996), 114(12), 1547-1551 (2007)
Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity
Journal of medicinal chemistry, 47(3), 530-549 (2004)
Brivaracetam attenuates pain behaviors in a murine model of neuropathic pain
Molecular Pain (2019)
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