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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
-10 to -25°C
SMILES字符串
[o]1c2c(cc3c(c2)OC([C@H](C3)OC(=O)\C(=C/C)\C)(C)C)cc[c]1=O
InChI
1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1
InChI key
AGABNGOXUSXQDD-XKGFZTIGSA-N
生化/生理作用
Decursinol Angelate is a pyranocoumarin isolated from medical plant Angelica gigas that exhibits potent anti-inflammatory properties. Decursinol Angelate appears to suppress type 17 helper T (Th17) cell responses in dextran sodium sulfate-induced colitis model. Decursinol Angelate reduces the production of NF-κB and COX-2 induced proinflammatory cytokine levels on TPA induced mice ear edema.
Main anti-inflammatory component of Angelica gigas extract
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Sukkum Ngullie Chang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 132, 110699-110699 (2019-07-28)
Decursinol angelate (DA) is a pyranocoumarin purified from the roots of Angelica gigas. Here, we synthesized DA and determined its anti-inflammatory potential on TPA-induced mice ear inflammation. First, we evaluated the non-toxic behaviour of DA on HaCaT cells. Additionally, we
Bikash Thapa et al.
Biomolecules & therapeutics, 27(5), 466-473 (2019-03-29)
Angelica gigas has been used as a Korean traditional medicine for pain relief and gynecological health. Although the extracts are reported to have an anti-inflammatory property, the bioactive compounds of the herbal plant and the effect on T cell responses
Salman Ul Islam et al.
Molecules (Basel, Switzerland), 23(8) (2018-08-01)
Inflammation is considered the root cause of various inflammatory diseases, including cancers. Decursinol angelate (DA), a pyranocoumarin compound obtained from the roots of Angelica gigas, has been reported to exhibit potent anti-inflammatory effects. In this study, the anti-inflammatory effects of
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