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Merck
CN

SML3259

Sigma-Aldrich

Morroniside

≥95% (HPLC)

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别名:
[1S-(1α,3β,4aβ,8β,8aβ)]-8-(β-D-Glucopyranosyloxy)-4,4a,8,8a-tetrahydro-3-hydroxy-1-methyl-1H,3H-Pyrano[3,4-c]pyran-5-carboxylic Acid Methyl Ester, b-Morroniside
经验公式(希尔记法):
C17H26O11
CAS号:
分子量:
406.38
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥95% (HPLC)

形式

powder

颜色

white to beige

储存温度

-10 to -25°C

生化/生理作用

Morroniside is a bioactive natural product with antioxidant and anti-inflammatory activity. Its activities have included protecttion against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression and regulation of hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Guoyong Zeng et al.
Experimental and therapeutic medicine, 16(3), 2229-2234 (2018-09-07)
The aim of the present study was to investigate the effect of morroniside against matrix metalloproteinase (MMP)2/9 and focal cerebral ischemia/reperfusion (I/R) injury in rats. A rat model of focal cerebral I/R injury rats was established and rats were administered
Lijuan Zhou et al.
Scientific reports, 8(1), 13785-13785 (2018-09-15)
Hair loss is characterized by a shortened hair anagen phase and hair follicles (HF) miniaturization. Morroniside is the most abundant iridoid glycoside extracted from Cornus officinalis and has various bioactivities in different cell functions and tissue regeneration. In this study
Kang Chen et al.
European journal of pharmacology, 834, 295-304 (2018-07-31)
Amyloid-β peptide (Aβ) plays a causal role in the development and progression of Alzheimer's disease (AD). Oxidative stress and activation of mitogen-activated protein kinase (MAPK) are involved in Aβ-induced neurotoxicity. Morroniside, one active monomer of dry ripe sarcocarp of Cornus

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