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Merck
CN

SML3255

Sigma-Aldrich

Crocetin

≥98% (HPLC)

别名:

α-Crocetin, 2,6,11,15-tetramethyl-2E,4E,6E,8E,10E,12E,14E-hexadecaheptaenedioic acid, NSC 407300, Trans-crocetin, Transcrocetin

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About This Item

经验公式(希尔记法):
C20H24O4
CAS号:
分子量:
328.40
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

faint brown to dark brown
deep red-brown

溶解性

DMSO: 2 mg/mL, clear

储存温度

−70°C

SMILES字符串

OC(=O)\C(=C\C=C\C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C(=O)O)\C)\C

InChI

1S/C20H24O4/c1-15(11-7-13-17(3)19(21)22)9-5-6-10-16(2)12-8-14-18(4)20(23)24/h5-14H,1-4H3,(H,21,22)(H,23,24)/b6-5+,11-7+,12-8+,15-9+,16-10+,17-13+,18-14+

InChI key

PANKHBYNKQNAHN-MQQNZMFNSA-N

生化/生理作用

Apocarotenoid dicarboxylic acid shown to exhibit antioxidant, antiproliferative, anti-inflammatory, cardioprotective, and antinociceptive activity.
Crocetin is a natural apocarotenoid dicarboxylic acid, found naturally in saffron crocus and gardenia flowers, that has been shown to exhibit antioxidant, antiproliferative, anti-inflammatory, cardioprotective, neuroprotective, and antinociceptive activity.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Eiji Inoue et al.
Journal of natural medicines, 72(1), 274-279 (2017-11-18)
Saffron, the stigma of Crocus sativus Linné (Iridaceae family), has been known to inhibit aggregation of β-amyloid, a nerve tissue protein. α-Synuclein (αS) is a 140-amino acid protein found abundantly in various regions of the brain. Its abnormal aggregation and
Maliheh Moradzadeh et al.
Journal of cellular physiology, 233(3), 2170-2182 (2017-04-14)
Natural products have gained a wide popularity as chemopreventive and anti-cancer agents owing to their multi-mechanistic mode of action, availability and synergism with several conventional chemotherapeutic agents. Crocetin is a carotenoid compound isolated from the stigma of Crocus sativus L.
Kyriaki Hatziagapiou et al.
Current neuropharmacology, 17(4), 377-402 (2018-03-23)
Reactive oxygen species and reactive nitrogen species, which are collectively called reactive oxygen-nitrogen species, are the inevitable by-products of cellular metabolic redox reactions, such as oxidative phosphorylation in the mitochondrial respiratory chain, phagocytosis, reactions of biotransformation of exogenous and endogenous

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