SML3080
C14PC
≥98% (HPLC)
别名:
2-[[Hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl- ethanaminium inner salt, CDI 166493, D 19390, FOS 14, Fos-choline 14, Tetradecylphosphocholine, n-Tetradecyl-phosphocholine, n-Tetradecylphosphocholine
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关于此项目
经验公式（希尔记法）:
C19H42NO4P
化学文摘社编号:
分子量:
379.51
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI
1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3
SMILES string
[O-]P(OCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)=O
InChI key
BETUMLXGYDBOLV-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
inhibitor of MARSA virulence
n-Tetradecylphosphocholine (C14PC), a more stable analog of myristoyl lysophosphatidylcholine, is an inhibitor of MARSA virulence. C14PC is a broad-spectrum inhibitor of Panton–Valentine leucocidin (PVL), LukED and α−toxin. C14PC protects primary human immune cells in vitro against cytolysis by PVL and α-toxin. C14PC can be used as a detergent for membrane solubilization.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Danyang Guo et al.
Metabolism: clinical and experimental, 107, 154232-154232 (2020-04-18)
Parasympathetic nerve (PN) signaling plays a crucial role in the maintenance of pancreatic β-cell volume density (Vβ). PN may be pathologically affected in diabetic polyneuropathy (DPN). However, the association between the reduction of PNs in islets and Vβ and the
Jie Liu et al.
The Journal of biological chemistry, 295(18), 5944-5959 (2020-03-18)
The rapid emergence and dissemination of methicillin-resistant Staphylococcus aureus (MRSA) strains poses a major threat to public health. MRSA possesses an arsenal of secreted host-damaging virulence factors that mediate pathogenicity and blunt immune defenses. Panton-Valentine leukocidin (PVL) and α-toxin are
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