所有图片(1)
别名:
N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)propionamide
经验公式（希尔记法）:
C15H14ClN5O
推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
ClC1=CNC2=NC=NC(NC3=CC=CC=C3NC(CC)=O)=C21
生化/生理作用
BSJ-04-122-R is a reversible control for a potent and selective covalent inhibitor of MKK4 and MKK7 BSJ-04-122. BSJ-04-122-R des not inhibit JNK phosphorylation.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Jie Jiang et al.
Cell chemical biology, 27(12), 1553-1560 (2020-09-12)
MKK4/7 are kinases that phosphorylate JNKs and regulate the MAPK signaling pathway. Their overexpression has been associated with tumorigenesis and aggressiveness in cancers such as breast, prostate, non-small cell lung, and pediatric leukemia, making them a potential target for inhibitor
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