推荐产品
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
O=C1C2=CC(O)=C(O)C=C2C3=C(C=C(O)C=C3)O1
InChI key
HHXMEXZVPJFAIJ-UHFFFAOYSA-N
生化/生理作用
Urolithin C is chebulic ellagitannins metabolite that exerts antiproliferative and antioxidant activity. Urolithin C exhibit glucose dependent enhancement of insulin secretion in islet cells under normal or dysfunctional conditions. Apparently, it facilitates L-type Ca2+ channel opening and Ca2+ influx into pancreatic β-cells.
chebulic ellagitannins metabolite, exhibit glucose dependent enhancement of insulin secretion
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Inhae Kang et al.
Molecular nutrition & food research, 60(5), 1129-1138 (2016-02-14)
Urolithins (Uro) are ellagic acid (EA)-derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary
Xudong Zeng et al.
American journal of translational research, 11(10), 6316-6325 (2019-11-19)
Cardiovascular diseases are the main cause of death and disability among diabetes patients. Atherosclerosis-associated stroke is one of the most severe complications in diabetes patients. DPP-4 inhibitors are a class of potent anti-glycemic agents used to treat diabetes. Recently, some
Daniil N Olennikov et al.
Nutrients, 7(10), 8456-8477 (2015-10-17)
Chebulic ellagitannins (ChET) are plant-derived polyphenols containing chebulic acid subunits, possessing a wide spectrum of biological activities that might contribute to health benefits in humans. The herbal formulation Padma Hepaten containing ChETs as the main phenolics, is used as a
Morgane Bayle et al.
British journal of pharmacology, 176(20), 4065-4078 (2019-08-06)
The pharmacology of polyphenol metabolites on beta-cell function is largely undetermined. We sought to identify polyphenol metabolites that enhance the insulin-secreting function of beta-cells and to explore the underlying mechanisms. INS-1 beta-cells and rat isolated islets of Langerhans or perfused
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