SML2963
8-氮鸟嘌呤
≥98% (HPLC)
别名:
2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散
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关于此项目
经验公式（希尔记法）:
C4H4N6O
化学文摘社编号:
分子量:
152.11
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
171098
MDL number:
NACRES:
NA.21
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
assay
≥98% (HPLC)
form
powder
color
white to beige
mp
>300 °C (lit.)
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
8-Azaguanine is a triazole-antimetabolite that displays varies pharmacological effects including anticancer, antiviral and antifungal. It is easily incorporated into ribonucleic acids including rRNA and tRNA. 8-Azaguanine appears to alter mRNA splicing in SF3B1 mutant cells. 8-Azaguanine novel immunomodulatory drug (IMiD) that significantly increases the cytotoxicity of NK cells.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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