推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
N(Cc2ccc(cc2)c3c(cccc3)C(=O)O)(c1ccccc1)C(=O)CCCC
InChI
1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)
InChI key
IUJTVDNJFPZYBL-UHFFFAOYSA-N
生化/生理作用
CAY10583 is a potent and selective full agonist for Leukotriene B4 receptor type 2 (BLT2). CAY10583 promotes wound healing and cell proliferation in cultured intestinal epithelial cells.
potent and selective full agonist for Leukotriene B4 receptor type 2 (BLT2)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Yoshiko Iizuka et al.
The Journal of biological chemistry, 280(26), 24816-24823 (2005-05-04)
Leukotriene B4 (LTB4) is a potent chemoattractant and activator for granulocytes and macrophages and is considered to be an inflammatory mediator. Two G-protein-coupled receptors for LTB4, BLT1 and BLT2, have been cloned from human and shown to be high and
Yui Matsumoto et al.
The Journal of pharmacology and experimental therapeutics, 373(1), 1-9 (2020-01-17)
Leukotriene B4 receptor type 2 (BLT2) is a low-affinity leukotriene B4 receptor that is highly expressed in intestinal epithelial cells. Previous studies demonstrated the protective role of BLT2 in experimentally induced colitis. However, its role in intestinal lesion repair is
Lin Luo et al.
Journal of diabetes and its complications, 31(1), 13-20 (2016-10-16)
The synthetic leukotriene B4 receptor type 2 (BLT2) agonist CAY10583 (CAY) accelerates wound healing in diabetic mice by promoting keratinocyte migration. However, its effects on fibroblast activity and granulation are unknown. We investigated the mechanisms by which CAY promotes wound
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门