推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
[Cl-].N3(CCCCC3)CCOc1ccc(cc1)C(=O)c2c(cccc2)C(=O)OC.[H+]
InChI
1S/C22H25NO4.ClH/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23;/h3-4,7-12H,2,5-6,13-16H2,1H3;1H
InChI key
ZRFIFDFEDPJBII-UHFFFAOYSA-N
生化/生理作用
Pitofenone is a potent muscarinic receptor antagonist. Pitofenone in combination with diclofenac exhibits potent antispasmodic effect in cholinergic spasm.
potent muscarinic receptor antagonist
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
J Sanahuja et al.
DICP : the annals of pharmacotherapy, 24(4), 361-364 (1990-04-01)
A comparative, randomized, double-blind study of diclofenac sodium 75 mg im versus Baralgin (a combination drug composed of dipyrone and two spasmolytics) 5 mL iv was performed on 57 patients with renal colic. Both groups were comparable as to age
K V Marthak et al.
Current medical research and opinion, 12(6), 366-373 (1991-01-01)
A single-blind, randomized clinical trial was carried out to compare the analgesic effectiveness in patients with renal colic of single intramuscular doses of diclofenac sodium (75 mg) versus a dipyrone (1 g)/spasmolytics combination, and diclofenac sodium (75 mg) versus pethidine
Shrinivas K Kulkarni et al.
Indian journal of experimental biology, 42(6), 567-569 (2004-07-21)
Biliary, ureteric and intestinal colic are extremely common clinical conditions associated with smooth muscle spasm. In the present study, antispasmodic activity was carried out against acetylcholine (10-640 ng/ml)-induced contractions on guinea pig ileum. Acetylcholine (10-640 ng/ml) induced concentration-dependent contraction of
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