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Merck
CN

SML2747

Forsythiaside A

≥98% (HPLC)

别名:

Forsythoside A, 2-(3,4-Dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]-β-D-glucopyranoside, Forsythiaside

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关于此项目

经验公式（希尔记法）:
C29H36O15
化学文摘社编号:
79916-77-1
分子量:
624.59
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD08460220

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产品名称

Forsythiaside A, ≥98% (HPLC)

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO[C@@H]4O[C@H]([C@@H]([C@H]([C@H]4O)O)O)C)OC(=O)\C=C\c3cc(c(cc3)O)O)O)O)OCCc2cc(c(cc2)O)O

InChI

1S/C29H36O15/c1-13-22(35)23(36)25(38)29(42-13)41-12-20-27(44-21(34)7-4-14-2-5-16(30)18(32)10-14)24(37)26(39)28(43-20)40-9-8-15-3-6-17(31)19(33)11-15/h2-7,10-11,13,20,22-33,35-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29+/m0/s1

InChI key

DTOUWTJYUCZJQD-UJERWXFOSA-N

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -25 to -17°, c = 1 in methanol

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Quality Level

100

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Biochem/physiol Actions

Forsythiaside A is a most abundant phenylethanoid glycosides isolated from Forsythia suspense that exhibits anti-inflammatory and neuroprotective activities. It appears that forsythoside A exerts antipyretic activities through inhibition of transient receptor potential vanilloid 1 (TRPV1) channel.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number
0000120024
0000120025
0000090052

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Quan-Jiang Song et al.
PloS one, 11(9), e0162791-e0162791 (2016-09-13)
Bovine viral diarrhea virus (BVDV), the causative agent of bovine viral diarrhea/mucosal disease (BVD/MD), is an important pathogen of cattle and other wild animals throughout the world. BVDV infection typically leads to an impaired immune response in cattle. In the
Cuiling Liu et al.
International journal of biological sciences, 13(1), 65-75 (2017-01-27)
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel gated by noxious heat, playing major roles in thermoregulation. Forsythoside A (FT-A) is the most abundant phenylethanoid glycosides in Fructus Forsythiae, which has been prescribed as a medicinal herb
Jin Qian et al.
European journal of pharmacology, 812, 250-255 (2017-07-25)
Forsythiaside A (FSA), an active constituent isolated from the Chinese medicinal herb Forsythia suspensa, has been known to have anti-inflammatory effect. However, the effect of FSA on allergic airway inflammation remains unclear. The aim of this study was to investigate

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