所有图片(1)
别名:
2-(2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-(1-(cyclopropylamino)-1,2-dioxohexan-3-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide, LY-570310, VX-950
经验公式（希尔记法）:
C36H53N7O6
推荐产品
检测方案
≥90% (HPLC)
形式
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
[H][C@@]1([C@@]2(CCC1)[H])CN(C([C@@H](NC([C@@H](NC(C3=NC=CN=C3)=O)C4CCCCC4)=O)C(C)(C)C)=O)[C@@H]2C(N[C@H](C(C(NC5CC5)=O)=O)CCC)=O
生化/生理作用
Telaprevir is a potent, selective and orally active hepatitis C virus (HCV) NS3.4A serine protease inhibitor. Telaprevir also inhibits chymotrypsin, chymase, elastase, and cathepsins F, K, L, S, and V in vitro
警示用语：
Warning
危险声明
危险分类
Repr. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Gema Méndez-Lagares et al.
Journal of immunology (Baltimore, Md. : 1950), 200(3), 1124-1132 (2017-12-22)
The contribution of the host immune system to the efficacy of new anti-hepatitis C virus (HCV) drugs is unclear. We undertook a longitudinal prospective study of 33 individuals with chronic HCV treated with combination pegylated IFN-α, ribavirin, and telaprevir/boceprevir. We
Robert B Perni et al.
Antimicrobial agents and chemotherapy, 50(3), 899-909 (2006-02-24)
VX-950 is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it demonstrated excellent antiviral activity both in genotype 1b HCV replicon cells (50% inhibitory concentration [IC50] = 354 nM) and in human fetal
Hiromitsu Kumada et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 48(2), 184-192 (2017-05-13)
To assess the efficacy and safety of telaprevir (TVR) when used in combination with natural human interferon-β (IFN-β) and ribavirin (RBV) for genotype 1 patients with depression compared to IFN-β/RBV therapy in Japan. We also examined the efficacy of the
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