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方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
N(c1c2c([o]c1C(=O)c3ccc(cc3)OC)cccc2)C(=O)C
InChI
1S/C18H15NO4/c1-11(20)19-16-14-5-3-4-6-15(14)23-18(16)17(21)12-7-9-13(22-2)10-8-12/h3-10H,1-2H3,(H,19,20)
InChI key
NQZBUYPGHZTWIR-UHFFFAOYSA-N
生化/生理作用
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 binds to valosin-containing protein (VCP)/p97.
inhibitor of cancer cell-enhanced fibroblast migration
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Kruthi Suvarna et al.
The Journal of biological chemistry, 294(9), 2988-2996 (2019-01-06)
Carcinoma-associated fibroblasts are fibroblasts activated by surrounding cancer cells. Carcinoma-associated fibroblasts exhibit enhanced cell migration, which plays an important role in cancer metastasis. Previously, we demonstrated enhanced migration of NIH3T3 fibroblasts when they were cultured in the presence of MCF7
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