检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear (warmed)
储存温度
2-8°C
InChI
1S/C21H25N.ClH/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21;/h5-8,10-14H,9,15H2,1-4H3;1H
InChI key
RADLXCPDUXFGFF-UHFFFAOYSA-N
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生化/生理作用
Melitracen is a tricyclic antidepressant (TCA) that likely exerts its in vivo efficacy similarly as imipramine and amitriptyline by inhibiting serotonin-norepinephrine reuptake.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jin-Ying Li et al.
World journal of gastrointestinal endoscopy, 9(12), 590-593 (2018-01-02)
Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett's esophagus on endoscopy and
The pharmacological properties of melitracen (N 7001) and litracen (N 7049).
I M Nielsen et al.
Arzneimittel-Forschung, 16(2), 135-140 (1966-02-01)
Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat.
K Shimamoto et al.
Acta Scholae Medicinalis Universitatis in Kioto, 40(1), 25-37 (1967-07-01)
Limin Wang et al.
BMC psychiatry, 15, 84-84 (2015-04-17)
Patients in chronic somatic diseases are often accompanied with depression and anxiety, remission of which may be observed in the third or fourth week after applying common antidepressant medications. We investigate the efficacy and safety of sertraline plus deanxit on
Studies on the metabolism of Melitracen (N 7001) in rats.
I Eberholst et al.
Arzneimittel-Forschung, 16(7), 876-878 (1966-07-01)
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