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COO原产地证书/COA分析证书

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SML2592

Arteether

Name: Arteether
Brand: SIGMA

≥95% (HPLC)

别名:

β-Arteether, (+)-Arteether, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, Dihydroartemisinin ethyl ether

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About This Item

经验公式（希尔记法）:

C₁₇H₂₈O₅

CAS号:

75887-54-6

分子量:

312.40

MDL编号:

MFCD00869355

UNSPSC代码:

51111800

NACRES:

NA.77

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方案

≥95% (HPLC)

表单

powder

旋光性

[α]/D +148 to +165°, c = 1 in chloroform-d

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

SMILES字符串

O1OC2(O[C@H]3O[C@@H]([C@@H]([C@H]4[C@]31[C@H]([C@@H](CC4)C)CC2)C)OCC)C

InChI

1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16?,17-/m1/s1

InChI key

NLYNIRQVMRLPIQ-BVCZABNKSA-N

生化/生理作用

Antimalarial artemisinin derivative

Arteether is a semisynthetic artemisinin derivative with antimalarial activity. It has been used for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria, and has also been shown to have anticancer activity.