SML2438
Magnolin
≥95% (HPLC)
别名:
Magnolin, (+)-Magnolin, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan, Medioresinol dimethyl ether, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
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所有图片(1)
About This Item
检测方案
≥95% (HPLC)
形式
powder
旋光性
[α]/D +46 to +56°, c = 0.5 in chloroform-d
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
[H][C@]12[C@]([C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC2)([H])CO[C@@H]1C4=CC=C(OC)C(OC)=C4
InChI
1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22+/m0/s1
InChI key
MFIHSKBTNZNJIK-RZTYQLBFSA-N
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生化/生理作用
Magnolin is a main component of Magnolia flos the exhibits anti-inflammatory, antioxidative, and vasodilatory activities. Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling. Also magnolin protects against renal tubular necrosis, apoptosis, and the deterioration of renal function in contrast-induced nephropathy (CIN) in rats.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Feng Wang et al.
Oxidative medicine and cellular longevity, 2014, 203458-203458 (2014-11-18)
Magnolin is the major active ingredient of the herb Magnolia fargesii which has anti-inflammatory and antioxidative effects. Oxidative stress and apoptosis are involved in the pathogenesis of contrast-induced nephropathy (CIN). We hypothesize that Magnolin could protect against CIN through antioxidative
Yeqing Huang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 87, 714-720 (2017-01-17)
Magnolin is the most active ingredient in the herb Magnolia fargesii, which has been traditionally used in oriental medicine to treat headaches and nasal congestion. Recent researches demonstrate that Magnolin inhibits cancer cell migration and invasion. This study used cell
Cheol-Jung Lee et al.
BMC cancer, 15, 576-576 (2015-08-09)
Magnolin is a natural compound abundantly found in Magnolia flos, which has been traditionally used in oriental medicine to treat headaches, nasal congestion and anti-inflammatory reactions. Our recent results have demonstrated that magnolin targets the active pockets of ERK1 and
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