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Merck
CN

SML2432

Sigma-Aldrich

Ethyl rosmarinate

≥98% (HPLC)

别名:

(αR)-α-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-benzenepropanoic acid ethyl ester, Rosmarinic acid ethyl ester, [R-(E)]-α-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid ethyl ester

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About This Item

经验公式(希尔记法):
C20H20O8
分子量:
388.37
UNSPSC代码:
12352200
NACRES:
NA.77

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated
protect from light

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

SMILES字符串

O=C(OCC)[C@H](OC(/C=C/C1=CC(O)=C(O)C=C1)=O)CC2=CC(O)=C(O)C=C2

InChI key

ROJRNQOAUDCMES-KRZKXXONSA-N

生化/生理作用

Ethyl rosmarinate is an anti-inflammatory and antioxidative compound present in Lycopus lucidus, Hyptis suaveolens and other medical plants that potently inhibits LPS induced production of nitric oxide and prostaglandin E2 in alveolar macrophages. Ethyl rosmarinate induces relaxation in aortic rings via an endothelium-independent pathway.
anti-inflammatory and antioxidative compound that potently inhibits LPS induced production of nitric oxide and prostaglandin E2 in alveolar macrophages

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Handan Gokben Sevindik et al.
Chemical & pharmaceutical bulletin, 63(9), 720-725 (2015-09-04)
Thymus praecox ssp. grossheimii (RONNIGER) JALAS var. grossheimii (Lamiaceae) is used as an herbal tea for cold, stomachache, cough, and infections in Turkey. There are no phytochemical studies on this species. We performed phytochemical studies and quantitative analysis of rosmarinic
Piyawadee Wicha et al.
European journal of pharmacology, 766, 9-15 (2015-09-13)
Ethyl rosmarinate is an ester derivative of rosmarinic acid, a major constituent of Hyptis suaveolens. The present study investigated the vasorelaxant mechanism of ethyl rosmarinate in isolated rat aortic rings using an organ bath system. Ethyl rosmarinate (0.1 µM-3mM) produced
Hathairat Thammason et al.
European journal of pharmacology, 824, 17-23 (2018-02-03)
In this study, a series of rosmarinic acid and analogs were investigated for their anti-inflammatory potential against LPS-induced alveolar macrophages (MH-S). Our results showed that, among the test compounds, ethyl rosmarinate (3) exhibited the most potent inhibitory effect on NO

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