所有图片(1)
别名:
(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-20-yn-3-one, Ethylnorgestrienone, R-2323, R2323, RU-2323
经验公式（希尔记法）:
C21H24O2
推荐产品
检测方案
≥97% (HPLC)
形式
powder
旋光性
[α]/D +81 to +88°, c = 0.4 in ethanol
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O[C@@]1(C#C)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3C=C[C@@]21CC)=O
InChI
1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
InChI key
BJJXHLWLUDYTGC-ANULTFPQSA-N
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生化/生理作用
Gestrinone is a synthetic steroid, an analog of norgestrienone, which exhibits androgenic, anti-estrogenic and anti-progestogenic activities. Gestrinone is used for treatment of endometriosis.
警示用语：
Warning
危险声明
危险分类
Repr. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Yan Zhu et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 66(8), 569-577 (2012-10-30)
The study was to investigate the effect of gestrinone on the growth of human uterine leiomyoma cells and on the levels and activity of p38, Src and estrogen receptor alpha (ERα). Human uterine leiomyoma cells were cultured and treated with
T Tamaya et al.
Acta obstetricia et gynecologica Scandinavica, 65(5), 439-441 (1986-01-01)
To understand the mechanism of biological action of gestrinone (R2323), which has a therapeutic effect against endometriosis, the binding of gestrinone to numerous classes of intracellular steroid binding proteins was studied in the human uterine endometrium. Gestrinone bound to endometrial
Alison K Death et al.
The Journal of clinical endocrinology and metabolism, 89(5), 2498-2500 (2004-05-06)
Tetrahydrogestrinone (THG) was recently identified as a novel steroid used illicitly to improve athletic performance. Although its structure is closely related to gestrinone, a 19-nor progestin, and resembles that of trenbolone, THG was never marketed, so information on its hormonal
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