检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
under inert gas
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
O[C@@H]1[C@@H](OC(CCC)=O)CN2[C@@]([C@@H](O)CC2)([H])[C@H]1O
InChI
1S/C12H21NO5/c1-2-3-9(15)18-8-6-13-5-4-7(14)10(13)12(17)11(8)16/h7-8,10-12,14,16-17H,2-6H2,1H3/t7-,8-,10+,11+,12+/m0/s1
InChI key
HTJGLYIJVSDQAE-VWNXEWBOSA-N
生化/生理作用
Celgosivir是天然双环亚氨基糖蓖麻精胺的前药，在体内表现出抗病毒活性，包括HCV和登革热。Celgosivir是α-葡萄糖苷酶的抑制剂，可抑制细胞培养物中的糖蛋白加工。 显然，抑制感染细胞内的α-葡萄糖苷酶可防止病毒分泌。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Andrew C Sayce et al.
PLoS neglected tropical diseases, 10(3), e0004524-e0004524 (2016-03-15)
It has long been thought that iminosugar antiviral activity is a function of inhibition of endoplasmic reticulum-resident α-glucosidases, and on this basis, many iminosugars have been investigated as therapeutic agents for treatment of infection by a diverse spectrum of viruses
Ilaria Vicenti et al.
SLAS discovery : advancing life sciences R & D, 25(5), 506-514 (2020-03-19)
Practical cell-based assays can accelerate anti-Zika (ZIKV) and anti-dengue (DENV) virus drug discovery. We developed an immunodetection assay (IA), using a pan-flaviviral monoclonal antibody recognizing a conserved envelope domain. The final protocol includes a direct virus yield reduction assay (YRA)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门