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Merck
CN

SML2284

Sigma-Aldrich

Mito A iodide

≥98% (HPLC)

别名:

3-(4’-Azidobenzamido)-prop-1-yl]triphenylphosphonium iodide

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About This Item

经验公式(希尔记法):
C28H26IN4OP
分子量:
592.41
UNSPSC代码:
12352200
NACRES:
NA.77

方案

≥98% (HPLC)

表单

powder

颜色

white to light brown

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES字符串

O=C(NCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(N=[N+]=[N-])C=C4.[I-]

InChI

1S/C28H25N4OP.HI/c29-32-31-24-19-17-23(18-20-24)28(33)30-21-10-22-34(25-11-4-1-5-12-25,26-13-6-2-7-14-26)27-15-8-3-9-16-27;/h1-9,11-20H,10,21-22H2;1H

InChI key

DMRSJCIHHULJSH-UHFFFAOYSA-N

生化/生理作用

MitoA is selective hydrogen sulfide (H2S) probe targeting mithchondria suitable for in vivo use. MitoA accumulates in mitochondria within tissues, where it is converted to MitoN by reaction with H2S. Both compounds are detected sensitively by LC-MS/MS.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Sabine Arndt et al.
The Journal of biological chemistry, 292(19), 7761-7773 (2017-03-23)
Hydrogen sulfide (H2S) is produced endogenously in vivo and has multiple effects on signaling pathways and cell function. Mitochondria can be both an H2S source and sink, and many of the biological effects of H2S relate to its interactions with

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